Glicómica Funcional y Molecular
Publicaciones
10/10/2021
Cancer letters
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)
Valeria da Costa, Sandra J van Vliet, Paula Carasi, Sofía Frigerio, Pablo A García, Diego O Croci, María Florencia Festari, Monique Costa, Mercedes Landeira, Santiago A Rodríguez-Zraquia, Alejandro J Cagnoni, Anabela M Cutine, Gabriel A Rabinovich, Eduardo Osinaga, Karina V Mariño, Teresa Freire
09/09/2021
Glycobiology
Tissue-specific control of galectin-1-driven circuits during inflammatory responses
Anabela M Cutine, Camila A Bach, Florencia Veigas, Joaquín P Merlo, Lorena Laporte, Montana N Manselle Cocco, Mora Massaro, Nicolas Sarbia, Ramiro M Perrotta, Yamil D Mahmoud, Gabriel A Rabinovich
15/08/2021
Bioorganic and medicinal chemistry
Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties
Cecilia Porciúncula-González, Alejandro J Cagnoni, Carolina Fontana, Karina V Mariño, Patricia Saenz-Méndez, Cecilia Giacomini, Gabriela Irazoqui
18/06/2021
Science Advances
Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits
Luciano G Morosi, Anabela M Cutine, Alejandro J Cagnoni, Montana N Manselle-Cocco, Diego O Croci, Joaquín P Merlo, Rosa M Morales, María May, Juan M Pérez-Sáez, María R Girotti, Santiago P Méndez-Huergo, Betiana Pucci, Aníbal H Gil, Sergio P Huernos, Guillermo H Docena, Alicia M Sambuelli, Marta A Toscano, Gabriel A Rabinovich, Karina V Mariño
01/06/2021
Apoptosis
Spatiotemporal regulation of galectin-1-induced T-cell death in lamina propria from Crohn’s disease and ulcerative colitis patients
Rodrigo Papa-Gobbi, Cecilia I Muglia, Andrés Rocca, Renata Curciarello, Alicia M Sambuelli, Martín Yantorno, Gustavo Correa, Luciano G Morosi, Antonio Di Sabatino, Paolo Biancheri, Thomas T MacDonald, Marta A Toscano, Karina V Mariño, Gabriel A Rabinovich, Guillermo H Docena
25/05/2021
Proceedings of the National Academy of Sciences
Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8 + regulatory T cells
Alejandro J Cagnoni, María Laura Giribaldi, Ada G Blidner, Anabela M Cutine, Sabrina G Gatto, Rosa M Morales, Mariana Salatino, Martín C Abba, Diego O Croci, Karina V Mariño, Gabriel A Rabinovich
01/02/2021
Angiogenesis
Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities
Juan M Pérez Sáez, Pablo F Hockl, Alejando J Cagnoni, Santiago P Méndez Huergo, Pablo A García, Sabrina G Gatto, Juan P Cerliani, Diego O Croci, Gabriel A Rabinovich
01/11/2020
Acta crystallographica. Section D, Structural biology
Crystal structures of peanut lectin in the presence of synthetic ?-N- and ?-S-galactosides disclose evidence for the recognition of different glycomimetic ligands
Alejandro J Cagnoni, Emiliano D Primo, Sebastián Klinke, María E Cano, Walter Giordano, Karina V Mariño, José Kovensky, Fernando A Goldbaum, María Laura Uhrig, Lisandro H Otero
