Neurobiología del Envejecimiento

Publicaciones

  • 26/07/2025

    Aging and disease

    Amyloid Beta Regulates Astrocytic Glucose Metabolism and Insulin Signaling in Experimental Models of Alzheimer’s Disease

    Melisa Bentivegna, Carlos Pomilio, Melina Bellotto, Nicolás González Pérez, Soledad P Rossi, Amal Gregosa, Daiana Vota, Fátima Merech, María Marta Bonaventura, Jessica Presa, Ángeles Vinuesa, Victoria Lux-Lantos, Soledad Porte Alcón, Flavia Saravia, Juan Beauquis

  • 08/06/2025

    Life sciences

    Metformin protects against insulin resistance-related dementia risk involving restored microglial homeostasis

    Nicolás González Pérez, Melina Bellotto, Soledad Porte Alcón, Melisa Bentivegna, Luciano Arcucci, Ángeles Vinuesa, Jessica Presa, Fernando Brites, Daniela Pérez Sirkin, Juan Beauquis, Flavia Saravia, Carlos Pomilio

  • Journal of Immunology

    20/03/2025

    The Journal of immunology

    Exacerbated endoplasmic reticulum stress transmitted by endometrial stromal cells alters the conditioning of tolerogenic dendritic cells affecting trophoblast migration

    Elizabeth Soczewski, Ana Schafir, Lara Castagnola, Lourdes Materazzi, Laura Fernández, Agustina Marcial, Jessica Presa, Flavia Saravia, Esteban Grasso, Daiana Vota, Claudia Pérez Leirós, Rosanna Ramhorst, Soledad Gori

  • Methods in molecular biology

    01/08/2024

    Molecular neurobiology

    Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer’s Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models

    C Pomilio, J Presa, C Oses, A Vinuesa, M Bentivegna, A Gregosa, M Riudavets, G Sevlever, V Galvan, V Levi, J Beauquis, F Saravia

  • 01/10/2023

    IBRO Neuroscience Reports

    Recovered astrocyte-vascular communication in the hippocampus of mice with cerebral amyloid angiopathy after glycan-binding protein Galectin-1 treatment

    Jessica Presa, Carlos Javier Pomilio, Amal Gregosa, Melisa Bentivegna, Nicolas Gonzalez Perez, Melina Bellotto, Mariano Soiza-Reilly, Juan Beauquis, Gabriel Rabinovich, Flavia Saravia

  • PLoS ONE

    26/09/2023

    PloS one

    Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors

    Shirley D Wenker, María Isabel Farias, Victoria Gradaschi, Corina Garcia, Juan Beauquis, María Celeste Leal, Carina Ferrari, Xianmin Zeng, Fernando J Pitossi

  • Sub-cellular biochemistry

    01/06/2022

    Geroscience

    Diabetic patients treated with metformin during early stages of Alzheimer’s disease show a better integral performance: data from ADNI study

    Carlos Pomilio, Nicolás González Pérez, Ismael Calandri, Lucía Crivelli, Ricardo Allegri, ADNI Alzheimer’s Disease Neuroimaging Initiative; Gustavo Sevlever, Flavia Saravia

  • Journal of neurochemistry

    01/05/2022

    Journal of neurochemistry

    A metabotropic glutamate receptor 3 (mGlu3R) isoform playing neurodegenerative roles in astrocytes is prematurely up-regulated in an Alzheimer’s model

    Juan Turati, Julieta Rudi, Juan Beauquis, Lila Carniglia, Federico López Couselo, Julieta Saba, Carla Caruso, Flavia Saravia, Mercedes Lasaga, Daniela Durand

  • Frontiers in Oncology

    23/04/2021

    Frontiers in Neuroscience

    Inflammation and Insulin Resistance as Risk Factors and Potential Therapeutic Targets for Alzheimer’s Disease

    Angeles Vinuesa, Carlos Pomilio, Amal Gregosa, Melisa Bentivegna, Jessica Presa, Melina Bellotto, Flavia Saravia, Juan Beauquis

  • Frontiers in Oncology

    25/09/2020

    Frontiers in Physiology

    Vasculo-Neuronal Coupling and Neurovascular Coupling at the Neurovascular Unit: Impact of Hypertension

    Jessica L Presa, Flavia Saravia, Zsolt Bagi, Jessica A Filosa