Neurobiologia del Envejecimiento


  • Methods in molecular biology


    Molecular neurobiology

    Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer’s Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models

    C Pomilio, J PresaC OsesA VinuesaM BentivegnaA GregosaM RiudavetsG SevleverV GalvanV LeviJ BeauquisF Saravia

  • PLoS ONE


    PloS one

    Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors

    Shirley D WenkerMaría Isabel FariasVictoria GradaschiCorina GarciaJuan BeauquisMaría Celeste LealCarina FerrariXianmin ZengFernando J Pitossi

  • Sub-cellular biochemistry



    Diabetic patients treated with metformin during early stages of Alzheimer’s disease show a better integral performance: data from ADNI study

    Carlos Pomilio, Nicolás González Pérez, Ismael Calandri, Lucía Crivelli, Ricardo Allegri, ADNI Alzheimer’s Disease Neuroimaging Initiative; Gustavo Sevlever, Flavia Saravia

  • Journal of neurochemistry


    Journal of neurochemistry

    A metabotropic glutamate receptor 3 (mGlu3R) isoform playing neurodegenerative roles in astrocytes is prematurely up-regulated in an Alzheimer’s model

    Juan Turati, Julieta Rudi, Juan Beauquis, Lila Carniglia, Federico López Couselo, Julieta Saba, Carla Caruso, Flavia Saravia, Mercedes Lasaga, Daniela Durand

  • Frontiers in Oncology


    Frontiers in Neuroscience

    Inflammation and Insulin Resistance as Risk Factors and Potential Therapeutic Targets for Alzheimer’s Disease

    Angeles Vinuesa, Carlos Pomilio, Amal Gregosa, Melisa Bentivegna, Jessica Presa, Melina Bellotto, Flavia Saravia, Juan Beauquis

  • Frontiers in Oncology


    Frontiers in Physiology

    Vasculo-Neuronal Coupling and Neurovascular Coupling at the Neurovascular Unit: Impact of Hypertension

    Jessica L Presa, Flavia Saravia, Zsolt Bagi, Jessica A Filosa

  • Molecular Human Reproduction


    Molecular Human Reproduction

    Platelet-derived Growth Factor B Restores Vascular Barrier Integrity and Diminishes Permeability in Ovarian Hyperstimulation Syndrome

    Natalia Pascuali, Leopoldina Scotti, Gonzalo Oubiña, Ignacio de Zúñiga, Gomez Peña, Carlos Pomilio, Flavia Saravia, Marta Tesone, Dalhia Abramovich, Fernanda Parborell

  • Geroscience



    Microglial autophagy is impaired by prolonged exposure to ?-amyloid peptides: evidence from experimental models and Alzheimer’s disease patients

    Pomilio C, Gorojod RM, Riudavets M, Vinuesa A, Presa J, Gregosa A, Bentivegna M, Alaimo A, Alcon SP, Sevlever G, Kotler ML, Beauquis J, Saravia F.

  • Consciousness and cognition


    Neurobiology of disease

    Periodic dietary restriction ameliorates amyloid pathology and cognitive impairment in PDAPP-J20 mice: Potential implication of glial autophagy

    Gregosa A, Vinuesa Á, Todero MF, Pomilio C, Rossi SP, Bentivegna M, Presa J, Wenker S, Saravia F, Beauquis J.

  • Methods in molecular biology


    Molecular neurobiology

    Early Exposure to a High-Fat Diet Impacts on Hippocampal Plasticity: Implication of Microglia-Derived Exosome-like Extracellular Vesicles

    Vinuesa A, Bentivegna M, Calfa G, Filipello F, Pomilio C, Bonaventura MM, Lux-Lantos V, Matzkin ME, Gregosa A, Presa J, Matteoli M, Beauquis J, Saravia F.