Several members of the Buffone Lab recently participated in the 2024 Annual Meeting of Bioscience Societies, jointly organized by the Argentine Society for Clinical Investigation (SAIC), the Argentine Society of Physiology (SAFIS), and the Latin American Association of Physiological Sciences (ALACF). The event took place from November 19 to 22 in Buenos Aires, Argentina. On Tuesday morning, during the Reproduction poster session, the following works were presented:

1. Lic. Pilar Ameijeiras presented

“Tracking Human Sperm Using Open-Source Machine Learning”.

Authors: Pilar Ameijeiras, Emily Kaplan, Adrián Pacheco Pozo, Haydee Hernández, Dario Krapf, Ana Romarowski, Diego Krapf, Mariano G. Buffone.

Awarded Best Poster in the Reproduction category.

2. Undergrad. Rita Celeste del Prado presented

“BSA-Mediated CatSper-Independent Rapid Calcium Uptake Initiates sAC Activation During Mouse Sperm Capacitation”.

Authors: Rita C. del Prado, Martina Jabloñski, Liza J. Schiavi-Ehrenhaus, Ana Romarowski, Alberto Darszon, Diego Krapf, Mariano G. Buffone, Guillermina M. Luque.

Later that afternoon, in another Reproduction poster session, Dr. Martina Jabloñski presented: “Identification and Characterization of Two Novel CatSper Inhibitors as Potential Non-Hormonal Male Contraceptives”. Authors: Martina Jabloñski, Lucila R. Gómez-Olivieri, Liza J. Schiavi-Ehrenhaus, Paula A. Balestrini, Analia G. Novero, Rita C. del Prado, Gerardo Orta, Alberto Darszon, Dario Krapf, Guillermina M. Luque, Mariano G. Buffone. On Wednesday afternoon, during the Reproduction oral session, the following presentations took place:

1. Undergrad. Sebastián Manikis presented

“Simultaneous High-Resolution Live Imaging of Cytoplasmic and Intracellular Calcium Store Dynamics in Progesterone-Induced Capacitated Mouse Sperm”.

Authors: Sebastián Manikis, Martina Griguoli, Martina Jabloñski, Pablo E. Visconti, Alberto Darszon, Mariano G. Buffone, Claudia Sánchez-Cárdenas, Ana Romarowski.

2. Lic. Lucila Rocío Gómez-Olivieri presented

“High-Throughput Screening Method for Discovering Novel CatSper Inhibitors Using Fluorescent Cell Barcoding and Intracellular Calcium Increase Caused by Membrane Depolarization and pH Alkalinization”.

Authors: Lucila R. Gómez-Olivieri, Martina Jabloñski, Liza J. Schiavi-Ehrenhaus, Mariano G. Buffone, Guillermina M. Luque.

Additionally, a study co-authored by several members of the Buffone Lab was presented:

3. Lic. Analia G. Novero presented

The Sodium-Proton Exchangers sNHE and NHE1 Control Plasma Membrane Hyperpolarization in Mouse Sperm”.

Authors: Analia G. Novero, Paulina Torres Rodríguez, José L. De la Vega Beltrán, Liza J. Schiavi-Ehrenhaus, Guillermina M. Luque, M. Carruba, Cintia Stival, Iñaki Gentile, Carla Ritagliati, Celia M. Santi, T. Nishigaki, Diego Krapf, Mariano G. Buffone, Alberto Darszon, Claudia L. Treviño, Dario Krapf.

Awarded Best Oral Presentation in the Reproduction category.

The participation of Buffone Lab members in this prestigious national congress, one of the most significant in clinical research, was an invaluable experience. It provided an opportunity to gain new knowledge, stay up to date with cutting-edge research, and reconnect with colleagues from across the country.