Molecular Oncology and New Therapeutic Targets

Lab publications

  • 06/12/2019

    Scientific Reports

    Association between high-fat diet feeding and male fertility in high reproductive performance mice

    Gómez-Elías MD, Rainero Cáceres TS, Giaccagli MM, Guazzone VA, Dalton GN, De Siervi A, Cuasnicú PS, Cohen DJ, Da Ros VG.

  • 18/09/2019

    Cell Death and Disease

    Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

    Byun JS, Park S, Yi DI, Shin JH, Hernandez SG, Hewitt SM, Nicklaus MC, Peach ML, Guasch L, Tang B, Wakefield LM, Yan T, Caban A, Jones A, Kabbout M, Vohra N, Nápoles AM, Singhal S, Yancey R, De Siervi A, Gardner K.

  • 01/04/2019

    Cell Death and Disease

    CTBP1 depletion on prostate tumors deregulates miRNA/mRNA expression and impairs cancer progression in metabolic syndrome mice

    Dalton GN, Massillo C, Scalise GD, Duca R, Porretti J, Farré PL, Gardner K, Paez A, Gueron G, De Luca P, De Siervi A.

  • International Journal of Cancer

    01/03/2019

    International Journal of Cancer

    CTBP1/CYP19A1/Estradiol axis together with adipose tissue impacts over prostate cancer growth associated to metabolic syndrome

    Massillo C, Dalton GN, Porretti J, Scalise GD, Farré PL, Piccioni F, Secchiari F, Pascuali N, Clyne C, Gardner K, De Luca P, De Siervi A.

  • Current Drug Targets

    01/01/2019

    Current pharmaceutical biotechnology

    Low Doses of CPS49 and Flavopiridol Combination as Potential Treatment for Advanced Prostate Cancer

    Zalazar F, Luca P, Gardner K, Figg WD, Meiss R, Spallanzani RG, Vallecorsa P, Elguero B, Cotignola J, Vazquez E, Siervi A.

  • International Journal of Cancer

    15/08/2018

    International Journal of Cancer

    CLCA2 epigenetic regulation by CTBP1, HDACs, ZEB1, EP300 and miR-196b-5p impacts prostate cancer cell adhesion and EMT in metabolic syndrome disease

    Porretti J, Dalton GN, Massillo C, Scalise GD, Farré PL, Elble R, Gerez EN, Accialini P, Cabanillas AM, Gardner K, De Luca P, De Siervi A.

  • Aging (Albany NY)

    13/02/2018

    Oncotarget

    CTBP1 and metabolic syndrome induce an mRNA and miRNA expression profile critical for breast cancer progression and metastasis

    Farré PL, Scalise GD, Duca RB, Dalton GN, Massillo C, Porretti J, Graña K, Gardner K, De Luca P, De Siervi A.

  • Reproduction

    01/10/2017

    Reproduction

    Implications of microRNA dysregulation in the development of prostate cancer

    Massillo C, Dalton GN, Farré PL, De Luca P, De Siervi A.

  • Aging (Albany NY)

    03/01/2017

    Oncotarget

    Improving risk stratification of patients with childhood acute lymphoblastic leukemia: Glutathione-S-Transferases polymorphisms are associated with increased risk of relapse

    Leonardi DB, Abbate M, Riccheri MC, Nuñez M, Alfonso G, Gueron G, De Siervi A, Vazquez E, Cotignola J.