There are many ovarian disorders that involve defects in vascular development (angiogenesis), such as anovulation and infertility, premature ovarian failure (POF), pregnancy loss, polycystic ovary syndrome (PCOS), and ovarian hyperstimulation syndrome (OHSS). If alterations in angiogenesis can be reversed in certain pathological conditions, it is possible that an improvement will also be achieved in these pathologies. Based on these considerations, the study of angiogenesis is of fundamental importance in the ovary in pathological conditions. In our laboratory, in order to establish therapeutic and diagnostic strategies, we use experimental models developed in rodents, cultures and cell lines, and human samples (ovarian cortices and follicular fluids). Therefore, one of the pillars of our laboratory is to permanently combine basic research in angiogenesis with clinical practice to improve ovarian functionality in cases of pathologies with altered angiogenesis with the aim of finding new therapies in these patients. Finally, to achieve this goal, in our laboratory we maintain a strong and constant collaboration with medical specialists in gynecology from public and private areas, promoting the appearance of translational medicine.