Molecular and Functional Glycomics

Glycosylation is one of the most common post-translational modifications: in eukaryotes, more than 50% of the proteins are glycosylated, and it’s estimated that around 0,5-1% of the human genome is dedicated to the biosynthesis or degradation of glycoconjugates. Structural analysis of these macromolecules in a certain organism (Glycomics), complements the information obtained through Proteomics and Genomics, providing a more realistic and integrated vision.

In our laboratory and through the establishment of a glycoanalytical platform, we study the structure of N- and O- glycans in glycoproteins. Our main interest is to capitalize on glycobiological mecanisms that could re-wire immune programs circuits, providing novel opportunities for translational medicine. From a biotechnological perspective and considering the relevance of glycosylation in biologicals and biotherapeutics, we offer services and consultancies on glycosylation analysis to the local and regional Life Sciences Industry.

Our main interest is to capitalize on glycobiological mecanisms that could re-wire immune programs circuits, providing novel opportunities for translational medicine.

From a biotechnological perspective and considering the relevance of glycosylation in biologicals and biotherapeutics, we offer services and consultancies on glycosylation analysis to the local and regional Life Sciences Industry.Our academic lines of research focus on characterizing the potential alteration of glycans and their relevance in the immune response, specifically in inflammatory bowel diseases and colorectal cancer.