Physiopathology of Innate Immunity
Lab publications
01/03/2023
Journal for immunotherapy of cancer
Blocking soluble TNFα sensitizes HER2-positive breast cancer to trastuzumab through MUC4 downregulation and subverts immunosuppression
Sofia Bruni, Florencia L Mauro, Cecilia J Proietti, Rosalia I Cordo-Russo, Martin A Rivas, Gloria Inurrigarro, Agustina Dupont, Dario Rocha, Elmer A Fernández, Ernesto Gil Deza, Daniel Lopez Della Vecchia, Sabrina Barchuk, Silvina Figurelli, David Lasso, Adrián D Friedrich, María C Santilli, María V Regge, Gabriel Lebersztein, Claudio Levit, Fabiana Anfuso, Teresa Castiglione, Patricia V Elizalde, Maria F Mercogliano, Roxana Schillaci
01/10/2022
Journal of allergy and clinical immunology
STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis
Simon J Pelham, Maria Soledad Caldirola, Danielle T Avery, Joseph Mackie, Geetha Rao, Florian Gothe, Timothy J Peters, Antoine Guerin, David Neumann, Doris Vokurkova, Vivian Hwa, Wenming Zhang, Shu-Chen Lyu, Iris Chang, Monali Manohar, Kari C Nadeau, Maria Isabel Gaillard, Liliana Bezrodnik, Violeta Iotova, Norberto Walter Zwirner, Mavel Gutierrez, Waleed Al-Herz, Christopher C Goodnow, Alexander Vargas Hernandez, Lisa Forbes, Sophie Hambleton, Elissa K Deenick, Cindy S Ma, Stuart G Tangye
03/08/2022
Oncoimmunology
The MICA-NKG2D axis in clear cell renal cell carcinoma bolsters MICA as target in immuno-oncology
Florencia Secchiari, Sol Yanel Nuñez, Jessica Mariel Sierra, Andrea Ziblat, María Victoria Regge, Ximena Lucía Raffo Iraolagoitia, Agustín Rovegno, Carlos Ameri, Fernando Pablo Secin, Nicolás Richards, Hernando Ríos Pita, Gonzalo Vitagliano, Luis Rico, Mauro Mieggi, Florencia Frascheri, Nicolás Bonanno, Leandro Blas, Aldana Trotta, Adrián David Friedrich, Mercedes Beatriz Fuertes, Carolina Inés Domaica, Norberto Walter Zwirner
12/11/2021
Frontiers in cell and developmental biology
Human Sperm Remain Motile After a Temporary Energy Restriction but do Not Undergo Capacitation-Related Events
Clara I Marín-Briggiler, Guillermina M Luque, María G Gervasi, Natalia Oscoz-Susino, Jessica M Sierra, Carolina Mondillo, Ana M Salicioni, Darío Krapf, Pablo E Visconti, Mariano G Buffone
20/09/2021
Frontiers in Immunology
Tumor-Experienced Human NK Cells Express High Levels of PD-L1 and Inhibit CD8 + T Cell Proliferation
Jessica M Sierra, Florencia Secchiari, Sol Y Nuñez, Ximena L Raffo Iraolagoitia, Andrea Ziblat, Adrián D Friedrich, María V Regge, M Cecilia Santilli, Nicolás I Torres, Mariana Gantov, Aldana Trotta, Carlos Ameri, Gonzalo Vitagliano, Hernando Ríos Pita, Luis Rico, Agustín Rovegno, Nicolás Richards, Carolina I Domaica, Norberto W Zwirner, Mercedes B Fuertes
04/06/2021
Frontiers in Immunology
Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1
Andrea Ziblat, Ximena Lucía Raffo Iraolagoitia, Sol Yanel Nuñez, Nicolás Ignacio Torres, Florencia Secchiari, Jessica Mariel Sierra, Raúl Germán Spallanzani, Agustín Rovegno, Fernando Pablo Secin, Mercedes Beatriz Fuertes, Carolina Inés Domaica, Norberto Walter Zwirner
01/06/2021
FASEB Journal
Membrane hyperpolarization abolishes calcium oscillations that prevent induced acrosomal exocytosis in human sperm
Paula A Balestrini, Claudia Sanchez-Cardenas, Guillermina M Luque, Carolina Baro Graf, Jessica M Sierra, Arturo Hernández-Cruz, Pablo E Visconti, Dario Krapf, Alberto Darszon, Mariano G Buffone