Tumor Physiology and Biology of the Ovary
In our laboratory we aim to study the mechanisms responsible for female fertility and the development of the follicle in the ovary. The ovarian follicle contains the oocyte and follicular cells, which produce the female sex hormones estradiol and progesterone. If the oocyte is fertilized, it is implanted in the uterine endometrium and ends in a successful birth. The principal function of the corpus luteum is the production of progesterone, an essential hormone for the preparation of the uterine endometrium where the embryo is implanted and develops. On the other hand, we investigate aspects related to the development and progression of ovarian cancer and the interaction of cancer cells with their tumor microenvironment. In this way, we aim to find solutions for cases in which the fertility of women is altered, and therapeutic strategies in patients with ovarian cancer.
Research area laboratories
Proteoglycan and Extracellular Matrix Chemistry
Dr. Juan Carlos Calvo
Molecular Oncology and New Therapeutic Targets
Dra. Adriana De Siervi
Nuclear Receptors
Dr. Mario D. Galigniana
Pharmaceutical Biotechnology
Dr. Gustavo Helguera
Hormonal Carcinogenesis
Dra. Claudia Lanari
Hormones and Cancer
Dra. Isabel Alicia Lüthy
Molecular and Functional Glycomics
Dra. Karina V. Mariño
Studies of the Physiopathology of the Ovary
Dra. María Fernanda Parborell
Glycomedicine
Dr. Gabriel Adrian Rabinovich
Tumor Immunology
Dra. Roxana Schillaci
Pathology and Molecular Pharmacology
Dra. Carina Shayo
Tumor Physiology and Biology of the Ovary
Dra. Marta Tesone
Cell-Cell Interaction Studies in Reproduction and Cancer
Dra. Mónica Hebe Vazquez-Levin
Stem Cells
Dr. Norma Alejandra Chasseing / Dr. Juan Carlos Calvo